Tumor epithelial cell matrix metalloproteinase 9 is a target for antimetastatic therapy in colorectal cancer.
BACKGROUND: The current paradigm suggests that matrix metalloproteinase 9 (MMP-9) expressed by stromal cells is a therapeutic target in human colorectal tumors which presumably regulates metastatic disease progression. Conversely, whereas cancer cells within those tumors may induce stromal cells to...
Main Authors: | Lubbe, W, Zhou, Z, Fu, W, Zuzga, D, Schulz, S, Fridman, R, Muschel, R, Waldman, SA, Pitari, G |
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Format: | Journal article |
Language: | English |
Published: |
2006
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