Tumor epithelial cell matrix metalloproteinase 9 is a target for antimetastatic therapy in colorectal cancer.

BACKGROUND: The current paradigm suggests that matrix metalloproteinase 9 (MMP-9) expressed by stromal cells is a therapeutic target in human colorectal tumors which presumably regulates metastatic disease progression. Conversely, whereas cancer cells within those tumors may induce stromal cells to...

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Bibliographic Details
Main Authors: Lubbe, W, Zhou, Z, Fu, W, Zuzga, D, Schulz, S, Fridman, R, Muschel, R, Waldman, SA, Pitari, G
Format: Journal article
Language:English
Published: 2006

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