Structural features underlying T-cell receptor sensitivity to concealed MHC class I micropolymorphisms.
Polymorphic differences distinguishing MHC class I subtypes often permit the presentation of shared epitopes in conformationally identical formats but can affect T-cell repertoire selection, differentially impacting autoimmune susceptibilities and viral clearance in vivo. The molecular mechanisms un...
| Auteurs principaux: | , , , , , , , |
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| Format: | Journal article |
| Langue: | English |
| Publié: |
2012
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