A computational model delineates differences in hydroxyapatite binding affinities of bisphosphonates in clinical use

A computational model delineates differences in hydroxyapatite binding affinities of bisphosphonates in clinical use

Մատենագիտական մանրամասներ
Հիմնական հեղինակներ:	Ebetino, E, Barnett, B, Russell, R
Ձևաչափ:	Conference item
Հրապարակվել է:	2005

Նմանատիպ նյութեր

A computational model explains bisphosphonate binding affinity differences on hydroxyapatite
‌: Ebetino, F, և այլն
Հրապարակվել է: (2006)

A computational model explains bisphosphonate binding affinity differences on hydroxyapatite
‌: Ebetino, F, և այլն
Հրապարակվել է: (2006)

Differences between bisphosphonates in binding affinities for hydroxyapatite.
‌: Lawson, M, և այլն
Հրապարակվել է: (2010)

Predicting the clinical potencies of bisphosphonates: Divergence of hydroxyapatite and farnesyl diphosphate synthase binding affinities
‌: Xia, Z, և այլն
Հրապարակվել է: (2007)

Nitrogen-containing bisphosphonates and prediction of their clinical potencies: Dissociation of target enzyme- and hydroxyapatite-binding affinities
‌: Xia, Z, և այլն
Հրապարակվել է: (2007)

Refining the use of hydroxyapatite column chromatography to reveal differences in relative binding affinities of bisphosphonates
‌: Lawson, M, և այլն
Հրապարակվել է: (2006)

Evaluation of the relative mineral-binding affinities of clinically-relevant bisphosphonates by hydroxyapatite-column chromatography
‌: Xia, Z, և այլն
Հրապարակվել է: (2008)

The use of hydroxyapatite column chromatography as a novel method to reveal differences in relative binding affinities of bisphosphonates
‌: Lawson, M, և այլն
Հրապարակվել է: (2005)

Mineral binding affinities of bisphosphonates.
‌: Nancollas, G, և այլն
Հրապարակվել է: (2002)

Mineral binding affinities and zeta potentials of bisphosphonates
‌: Nancollas, G, և այլն
Հրապարակվել է: (2002)

Determination of the relative bone mineral-binding affinities of bisphosphonates by using hydroxyapatite-column chromatography combined with mass spectrometric analysis
‌: Duan, X, և այլն
Հրապարակվել է: (2010)

Potential bone mineral binding differences among bisphosphonates can be demonstrated by the use of hydroxyapatite column chromatography.
‌: Lawson, M, և այլն
Հրապարակվել է: (2005)

Comparative mineral binding affinities of selected bisphosphonates
‌: Nancollas, G, և այլն
Հրապարակվել է: (2002)

Bisphosphonate bone affinity, differences predicted by in vitro binding to carbonated apatite
‌: Henneman, Z, և այլն
Հրապարակվել է: (2004)

Predicting pharmacological potencies of nitrogen-containing bisphosphonates; novel methods dissociate enzyme- and hydroxyapatite-binding affinities
‌: Xia, Z, և այլն
Հրապարակվել է: (2007)

A novel method to characterize relative mineral binding affinities of bisphosphonates and the structural requirements for binding by using ceramic hydroxyapatite column chromatography.
‌: Xia, Z, և այլն
Հրապարակվել է: (2006)

Evaluation of the relative mineral-binding affinities of clinically-relevant bisphosphonates by using hydroxyapatite-column chromatography and adsorption isotherms combined with mass spectrometric analysis
‌: Xia, Z, և այլն
Հրապարակվել է: (2008)

Bisphosphonate binding affinity as assessed by inhibition of carbonated apatite dissolution in vitro.
‌: Henneman, Z, և այլն
Հրապարակվել է: (2008)

BONE AFFINITY DIFFERENCES OF NITROGEN-CONTAINING BISPHOSPHONATES PREDICTED BY IN VITRO BINDING TO CARBONATED APATITE
‌: Ebetino, F, և այլն
Հրապարակվել է: (2004)

Bisphosphonate affinity to hydroxyapatite and farnesyl pyrophosphate inhibitory potency, together, drive in vivo efficacy
‌: Lundy, M, և այլն
Հրապարակվել է: (2007)

NE‐58025: A bisphosphonate with a low hydroxyapatite binding affinity
‌: Michael Pazianas
Հրապարակվել է: (2021-08-01)

Bisphosphonate bone affinity, differences predicted by in vitro carbonated apatite model.
‌: Henneman, Z, և այլն
Հրապարակվել է: (2003)

Novel insights into actions of bisphosphonates on bone: differences in interactions with hydroxyapatite.
‌: Nancollas, G, և այլն
Հրապարակվել է: (2006)

Modeling of bisphosphonate binding to farnesyl diphosphate synthase
‌: Ebetino, F, և այլն
Հրապարակվել է: (2002)

A Bisphosphonate With a Low Hydroxyapatite Binding Affinity Prevents Bone Loss in Mice After Ovariectomy and Reverses Rapidly With Treatment Cessation
‌: Abigail A Coffman, և այլն
Հրապարակվել է: (2021-04-01)

Synthesis of novel bisphosphonate polyamine conjugates and their affinity to hydroxyapatite
‌: Elina Sankala, և այլն
Հրապարակվել է: (2012-02-01)

Reply to: A Bisphosphonate With a Low Hydroxyapatite Binding Affinity Prevents Bone Loss in Mice After Ovariectomy and Reverses Rapidly With Treatment Cessation
‌: Abigail A Coffman, և այլն
Հրապարակվել է: (2021-07-01)

The Successful Design Of A Novel Highly Potent Nitrogen-Containing Bisphosphonate With Lower Bone Affinity.
‌: Ebetino, F, և այլն
Հրապարակվել է: (2013)

Bisphosphonate binding affinity affects drug distribution in both intracortical and trabecular bone of rabbits.
‌: Turek, J, և այլն
Հրապարակվել է: (2012)

Refining structure activity relationships among nitrogen containing bisphosphonates: Dissociation of mineral binding affinity and inhibitory potency on farnesyl diphosphate synthase.
‌: Xia, Z, և այլն
Հրապարակվել է: (2006)

Bone mineral affinity influences the distribution of a bisphosphonate and a lower affinity analogue in vivo
‌: Roelofs, A, և այլն
Հրապարակվել է: (2009)

Mechanisms of action of bisphosphonates: similarities and differences and their potential influence on clinical efficacy.
‌: Russell, R, և այլն
Հրապարակվել է: (2008)

Differentiation of bisphosphonates based on their physical chemical properties
‌: Phipps, R, և այլն
Հրապարակվել է: (2006)

The mode of binding of nitrogen containing bisphosphonates in farnesyl pyrophosphate synthase
‌: Ebetino, F, և այլն
Հրապարակվել է: (2007)

A mirror image pair of bisphosphonate analogs further demonstrates the mode of binding of the bisphosphonates in farnesyl pyrophosphate synthase
‌: Ebetino, F, և այլն
Հրապարակվել է: (2008)

Influence of bone affinity on the skeletal distribution of fluorescently labeled bisphosphonates in vivo.
‌: Roelofs, A, և այլն
Հրապարակվել է: (2012)

Analysis of mineral binding activities of bisphosphonates by using hydroxyapatite chromatography and adsorption isotherms together with detection by light absorption, fluorescence derivatisation and tandem mass spectrometry
‌: Xia, Z, և այլն
Հրապարակվել է: (2008)

Differences in the potential binding of phosphate containing compounds to bone mineral are revealed by the novel use of hydroxyapatite column chromatography
‌: Lawson, M, և այլն
Հրապարակվել է: (2005)

The Ability of Bisphosphonates and Their Analogues to Penetrate the Osteocyte Network is Dependent on Affinity for Bone
‌: Roelofs, A, և այլն
Հրապարակվել է: (2010)

Molecular modeling of the bisphosphonates (BPs) in farnesyl diphosphate (FPP) synthase. Proposed new mechanism of inhibition by potent nitrogen containing bisphosphonates (NBPs).
‌: Ebetino, F, և այլն
Հրապարակվել է: (2002)