Exposure-response relationships in asthma caused by tetrachlorophthalic anhydride.

Four patients with asthma caused by occupational exposure to tetrachlorophthalic anhydride (TCPA) had dust-challenge tests that used eight different levels of TCPA exposure. Measurements of TCPA in the test-cubicle air ranged from 1.3 to 961.1 micrograms/m3. The higher exposures provoked definite la...

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Библиографические подробности
Главные авторы: Venables, K, Newman Taylor, A
Формат: Journal article
Язык:English
Опубликовано: 1990
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author Venables, K
Newman Taylor, A
author_facet Venables, K
Newman Taylor, A
author_sort Venables, K
collection OXFORD
description Four patients with asthma caused by occupational exposure to tetrachlorophthalic anhydride (TCPA) had dust-challenge tests that used eight different levels of TCPA exposure. Measurements of TCPA in the test-cubicle air ranged from 1.3 to 961.1 micrograms/m3. The higher exposures provoked definite late or dual asthmatic responses. Smaller, but statistically significant, responses were observed at low exposures. The late asthmatic-response area had a linear relation to the logarithm of TCPA exposure, but the immediate asthmatic response was less closely related to exposure.
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spelling oxford-uuid:f86ad99c-1569-496a-895d-278c32b5a1142022-03-27T12:50:03ZExposure-response relationships in asthma caused by tetrachlorophthalic anhydride.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:f86ad99c-1569-496a-895d-278c32b5a114EnglishSymplectic Elements at Oxford1990Venables, KNewman Taylor, AFour patients with asthma caused by occupational exposure to tetrachlorophthalic anhydride (TCPA) had dust-challenge tests that used eight different levels of TCPA exposure. Measurements of TCPA in the test-cubicle air ranged from 1.3 to 961.1 micrograms/m3. The higher exposures provoked definite late or dual asthmatic responses. Smaller, but statistically significant, responses were observed at low exposures. The late asthmatic-response area had a linear relation to the logarithm of TCPA exposure, but the immediate asthmatic response was less closely related to exposure.
spellingShingle Venables, K
Newman Taylor, A
Exposure-response relationships in asthma caused by tetrachlorophthalic anhydride.
title Exposure-response relationships in asthma caused by tetrachlorophthalic anhydride.
title_full Exposure-response relationships in asthma caused by tetrachlorophthalic anhydride.
title_fullStr Exposure-response relationships in asthma caused by tetrachlorophthalic anhydride.
title_full_unstemmed Exposure-response relationships in asthma caused by tetrachlorophthalic anhydride.
title_short Exposure-response relationships in asthma caused by tetrachlorophthalic anhydride.
title_sort exposure response relationships in asthma caused by tetrachlorophthalic anhydride
work_keys_str_mv AT venablesk exposureresponserelationshipsinasthmacausedbytetrachlorophthalicanhydride
AT newmantaylora exposureresponserelationshipsinasthmacausedbytetrachlorophthalicanhydride