NF-kappaB-inducing kinase is dispensable for activation of NF-kappaB in inflammatory settings but essential for lymphotoxin beta receptor activation of NF-kappaB in primary human fibroblasts.
The transcription factor NF-kappaB is of major importance in the biology of pro-inflammatory cytokines, such as TNF-alpha and IL-1alpha, and thereby is intimately involved in the process of inflammation. Understanding the mechanisms by which NF-kappaB is activated in response to inflammatory stimuli...
मुख्य लेखकों: | Smith, C, Andreakos, E, Crawley, J, Brennan, F, Feldmann, M, Foxwell, B |
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स्वरूप: | Journal article |
भाषा: | English |
प्रकाशित: |
2001
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समान संसाधन
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Activation of NF-kappaB by the intracellular expression of NF-kappaB-inducing kinase acts as a powerful vaccine adjuvant.
द्वारा: Andreakos, E, और अन्य
प्रकाशित: (2006) -
VEGF expression in human macrophages is NF-kappaB-dependent: studies using adenoviruses expressing the endogenous NF-kappaB inhibitor IkappaBalpha and a kinase-defective form of the IkappaB kinase 2.
द्वारा: Kiriakidis, S, और अन्य
प्रकाशित: (2003) -
VEGF expression in human macrophages is NF-kappaB-dependent: studies using adenoviruses expressing the endogenous NF-kappaB inhibitor IkappaBalpha and a kinase-defective form of the IkappaB kinase 2.
द्वारा: Kiriakidis, S, और अन्य
प्रकाशित: (2003) -
Is NF-kappaB a useful therapeutic target in rheumatoid arthritis?
द्वारा: Feldmann, M, और अन्य
प्रकाशित: (2002) -
NF-kappaB mediates tumor necrosis factor alpha-induced expression of optineurin, a negative regulator of NF-kappaB.
द्वारा: Cherukuri Sudhakar, और अन्य
प्रकाशित: (2009-01-01)