Structural basis and specificity of human otubain 1-mediated deubiquitination.

Structural basis and specificity of human otubain 1-mediated deubiquitination.

OTUB (otubain) 1 is a human deubiquitinating enzyme that is implicated in mediating lymphocyte antigen responsiveness, but whose molecular function is generally not well defined. A structural analysis of OTUB1 shows differences in accessibility to the active site and in surface properties of the sub...

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Hlavní autoři: Edelmann, M, Iphöfer, A, Akutsu, M, Altun, M, di Gleria, K, Kramer, H, Fiebiger, E, Dhe-Paganon, S, Kessler, B
Médium: Journal article
Jazyk:English
Vydáno: 2009

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