Structural basis and specificity of human otubain 1-mediated deubiquitination.

Structural basis and specificity of human otubain 1-mediated deubiquitination.

OTUB (otubain) 1 is a human deubiquitinating enzyme that is implicated in mediating lymphocyte antigen responsiveness, but whose molecular function is generally not well defined. A structural analysis of OTUB1 shows differences in accessibility to the active site and in surface properties of the sub...

書誌詳細
主要な著者:	Edelmann, M, Iphöfer, A, Akutsu, M, Altun, M, di Gleria, K, Kramer, H, Fiebiger, E, Dhe-Paganon, S, Kessler, B
フォーマット:	Journal article
言語:	English
出版事項:	2009

類似資料

Post-translational modification of the deubiquitinating enzyme otubain 1 modulates active RhoA levels and susceptibility to Yersinia invasion.
著者:: Edelmann, M, 等
出版事項: (2010)

Biochemical characterization of a novel deubiquitinating enzyme otubain 1 and investigation into its role in Yersinia infection
著者:: Edelmann, M, 等
出版事項: (2010)

The human otubain2-ubiquitin structure provides insights into the cleavage specificity of poly-ubiquitin-linkages
著者:: Altun, M, 等
出版事項: (2015)

Otubains
著者:: Kessler, B
出版事項: (2013)

Fluorescence-based active site probes for profiling deubiquitinating enzymes.
著者:: McGouran, J, 等
出版事項: (2012)

The otubain YOD1 is a deubiquitinating enzyme that associates with p97 to facilitate protein dislocation from the ER
著者:: Ploegh, Hidde, 等
出版事項: (2009)

Deubiquitinating enzyme specificity for ubiquitin chain topology profiled by di-ubiquitin activity probes.
著者:: McGouran, J, 等
出版事項: (2013)

Profiling ubiquitin linkage specificities of deubiquitinating enzymes with branched ubiquitin isopeptide probes.
著者:: Iphöfer, A, 等
出版事項: (2012)

PTMs in conversation: activity and function of deubiquitinating enzymes regulated via post-translational modifications.
著者:: Kessler, B, 等
出版事項: (2011)

PTMs in Conversation: Activity and Function of Deubiquitinating Enzymes Regulated via Post-Translational Modifications
著者:: Kessler, B, 等
出版事項: (2011)

Otubain 2 promotes muramyl dipeptide‐mediated anti‐colitogenic effects due to de‐ubiquitination of receptor interaction protein 2
著者:: Jochen Mattner
出版事項: (2024-10-01)

Oligomeric structure of the MALT1 tandem Ig-like domains.
著者:: Liyan Qiu, 等
出版事項: (2011-01-01)

Structural and Functional Basis of JAMM Deubiquitinating Enzymes in Disease
著者:: Xin Pan, 等
出版事項: (2022-06-01)

Knockdown of otubain 2 inhibits liver cancer cell growth by suppressing NF‐κB signaling
著者:: Zhen‐Lin Gu, 等
出版事項: (2020-06-01)

Deubiquitination complex platform: A plausible mechanism for regulating the substrate specificity of deubiquitinating enzymes
著者:: Yi-Zheng Fang, 等
出版事項: (2023-07-01)

Structures of human DPP7 reveal the molecular basis of specific inhibition and the architectural diversity of proline-specific peptidases.
著者:: Gustavo Arruda Bezerra, 等
出版事項: (2012-01-01)

Molecular basis for recognition and deubiquitination of 40S ribosomes by Otu2
著者:: Ken Ikeuchi, 等
出版事項: (2023-05-01)

USP10 deubiquitinates Tau, mediating its aggregation
著者:: Zhen Wei, 等
出版事項: (2022-08-01)

Partial otubain 1 deficiency compromises fetal well-being in allogeneic pregnancies despite no major changes in the dendritic cell and T cell compartment
著者:: Annika Stutz, 等
出版事項: (2022-11-01)

Extended peptide-based inhibitors efficiently target the proteasome and reveal overlapping specificities of the catalytic beta-subunits.
著者:: Kessler, B, 等
出版事項: (2001)

The ubiquitin‐specific protease 5 mediated deubiquitination of LSH links metabolic regulation of ferroptosis to hepatocellular carcinoma progression
著者:: Bokang Yan, 等
出版事項: (2023-08-01)

Ubiquitin and ubiquitin-like specific proteases targeted by infectious pathogens: Emerging patterns and molecular principles.
著者:: Edelmann, M, 等
出版事項: (2008)

Comprehensive Landscape of Active Deubiquitinating Enzymes Profiled by Advanced Chemoproteomics
著者:: Adán Pinto-Fernández, 等
出版事項: (2019-08-01)

Deubiquitinating Enzymes and Bone Remodeling
著者:: Yu-chen Guo, 等
出版事項: (2018-01-01)

Ankylosing spondylitis monocytes show upregulation of proteins involved in inflammation and the ubiquitin proteasome pathway.
著者:: Wright, C, 等
出版事項: (2009)

Recent Progress of Deubiquitinating Enzymes in Human and Plant Pathogenic Fungi
著者:: Weixiang Wang, 等
出版事項: (2022-10-01)

Comprehensive Landscape of Active Deubiquitinating Enzymes Profiled by Advanced Chemoproteomics
著者:: Pinto-Fernández, A, 等
出版事項: (2019)

OTUD4-mediated GSDME deubiquitination enhances radiosensitivity in nasopharyngeal carcinoma by inducing pyroptosis
著者:: Muping Di, 等
出版事項: (2022-11-01)

FKBP family proteins : immunophilins with versatile biological functions
著者:: Kang, Cong Bao, 等
出版事項: (2012)

Accelerating inhibitor discovery for deubiquitinating enzymes
著者:: Wai Cheung Chan, 等
出版事項: (2023-02-01)

Structural basis for defective membrane targeting of mutant enzyme in human VLCAD deficiency
著者:: Michelle S. Prew, 等
出版事項: (2022-06-01)

USP47-mediated deubiquitination and stabilization of YAP contributes to the progression of colorectal cancer
著者:: Beiqing Pan, 等
出版事項: (2019-11-01)

ATR-Mediated FANCI Phosphorylation Regulates Both Ubiquitination and Deubiquitination of FANCD2
著者:: Winnie Tan, 等
出版事項: (2020-02-01)

A genomic and functional inventory of deubiquitinating enzymes.
著者:: Nijman, S, 等
出版事項: (2005)

Ubiquitin-specific protease 29 attenuates hepatic ischemia-reperfusion injury by mediating TGF-β-activated kinase 1 deubiquitination
著者:: Zhongbao Chen, 等
出版事項: (2023-05-01)

Operative ubiquitin-specific protease 22 deubiquitination confers a more invasive phenotype to cholangiocarcinoma
著者:: Tian, Y, 等
出版事項: (2021)

Chemistry-based functional proteomics reveals novel members of the deubiquitinating enzyme family.
著者:: Borodovsky, A, 等
出版事項: (2002)

Syndecan-4 negatively regulates antiviral signalling by mediating RIG-I deubiquitination via CYLD
著者:: Wei Lin, 等
出版事項: (2016-06-01)

Systematic analysis of the physiological importance of deubiquitinating enzymes.
著者:: Wei-Ling Tsou, 等
出版事項: (2012-01-01)

Specific Deubiquitinating Enzymes Promote Host Restriction Factors Against HIV/SIV Viruses
著者:: Wenying Gao, 等
出版事項: (2021-09-01)