Towards the genomic sequence code of DNA fragility for machine learning

Genomic DNA breakages and the subsequent insertion and deletion mutations are important contributors to genome instability and linked diseases. Unlike the research in point mutations, the relationship between DNA sequence context and the propensity for strand breaks remains elusive. Here, by analyzi...

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Príomhchruthaitheoirí: Pflughaupt, P, Abdullah, A, Masuda, K, Sahakyan, A
Formáid: Journal article
Teanga:English
Foilsithe / Cruthaithe: Oxford University Press 2024