Principles of dimer-specific gene regulation revealed by a comprehensive characterization of NF-κB family DNA binding.

Principles of dimer-specific gene regulation revealed by a comprehensive characterization of NF-κB family DNA binding.

Show other versions (1)

The unique DNA-binding properties of distinct NF-κB dimers influence the selective regulation of NF-κB target genes. To more thoroughly investigate these dimer-specific differences, we combined protein-binding microarrays and surface plasmon resonance to evaluate DNA sites recognized by eight differ...

Full description

Bibliographic Details
Main Authors:	Siggers, T, Chang, AB, Teixeira, A, Wong, D, Williams, K, Ahmed, B, Ragoussis, J, Udalova, I, Smale, S, Bulyk, M
Format:	Journal article
Language:	English
Published:	2012

Similar Items

Principles of dimer-specific gene regulation revealed by a comprehensive characterization of NF-κB family DNA binding
by: Siggers, T, et al.
Published: (2012)

Extensive characterization of NF-κB binding uncovers non-canonical motifs and advances the interpretation of genetic functional traits.
by: Wong, D, et al.
Published: (2011)

Extensive characterization of NF-κB binding uncovers non-canonical motifs and advances the interpretation of genetic functional traits
by: Wong, Daniel, et al.
Published: (2012)

Cross-species analysis reveals evolving and conserved features of the nuclear factor κB (NF-κB) proteins.
by: Ryzhakov, G, et al.
Published: (2013)

Non-DNA-binding cofactors enhance DNA-binding specificity of a transcriptional regulatory complex
by: Siggers, Trevor, et al.
Published: (2013)

The Transcriptional Specificity of NF-κB Dimers Is Coded within the κB DNA Response Elements
by: Vivien Ya-Fan Wang, et al.
Published: (2012-10-01)

Quantitative profiling of protein-DNA binding on microarrays.
by: Ragoussis, J, et al.
Published: (2006)

Targeting DNA Binding for NF-κB as an Anticancer Approach in Hepatocellular Carcinoma
by: Po Yee Chung, et al.
Published: (2018-10-01)

Structures of NF-κB p52 homodimer-DNA complexes rationalize binding mechanisms and transcription activation
by: Wenfei Pan, et al.
Published: (2023-02-01)

An improved SELEX-Seq strategy for characterizing DNA-binding specificity of transcription factor: NF-κB as an example.
by: Guangming Gu, et al.
Published: (2013-01-01)

NF-κB fingerprinting reveals heterogeneous NF-κB composition in diffuse large B-cell lymphoma
by: Eleanor Jayawant, et al.
Published: (2023-06-01)

Context influences on TALE–DNA binding revealed by quantitative profiling
by: Rogers, Julia M., et al.
Published: (2015)

Survey of variation in human transcription factors reveals prevalent DNA binding changes
by: Vedenko, A., et al.
Published: (2017)

Comparison of NF-κB from the protists Capsaspora owczarzaki and Acanthoeca spectabilis reveals extensive evolutionary diversification of this transcription factor
by: Leah M. Williams, et al.
Published: (2021-12-01)

Comparing the fine specificity of DNA binding by NF-kappaB p50 and p52 using principal coordinates analysis.
by: Nijnik, A, et al.
Published: (2003)

Leocarpinolide B Attenuates Collagen Type II-Induced Arthritis by Inhibiting DNA Binding Activity of NF-κB
by: Ke-Gang Linghu, et al.
Published: (2023-05-01)

DNA-dependent protein kinase catalytic subunit binds to the transactivation domain 1 of NF-κB p65
by: Yuta Hasegawa, et al.
Published: (2023-09-01)

Thioredoxin-1 distinctly promotes NF-κB target DNA binding and NLRP3 inflammasome activation independently of Txnip
by: Jonathan Muri, et al.
Published: (2020-02-01)

Accuracy and reproducibility of protein-DNA microarray technology.
by: Field, S, et al.
Published: (2007)

Accuracy and reproducibility of protein-DNA microarray technology
by: Field, S, et al.
Published: (2006)

DNA damage independent inhibition of NF-κB transcription by anthracyclines
by: Angelo Ferreira Chora, et al.
Published: (2022-12-01)

Quantitative prediction of NF-kappa B DNA-protein interactions.
by: Udalova, I, et al.
Published: (2002)

EHMT1 binds to NF-κB p50 and represses gene expression.
by: Ea, C.K., et al.
Published: (2012)

NF-κB/c-Rel DNA-binding is reduced in substantia nigra and peripheral blood mononuclear cells of Parkinson's disease patients
by: Vanessa Porrini, et al.
Published: (2023-05-01)

The NF-κB Genomic Landscape in Lymphoblastoid B Cells
by: Zhao, Bo, et al.
Published: (2016)

N-acetyldopamine dimer inhibits neuroinflammation through the TLR4/NF-κB and NLRP3/Caspase-1 pathways
by: Huang Lijun, et al.
Published: (2022-08-01)

Interaction of AP-1 with a cluster of NF-kappa B binding elements in the human TNF promoter region.
by: Udalova, I, et al.
Published: (2001)

NF-κB and Disease
by: Paola Poma
Published: (2020-12-01)

Starvation decreases immunity and immune regulatory factor NF-κB in the starlet sea anemone Nematostella vectensis
by: Pablo J. Aguirre Carrión, et al.
Published: (2023-07-01)

Combinatorial bZIP dimers display complex DNA-binding specificity landscapes
by: Rodriguez-Martinez, Jose A., et al.
Published: (2017)

NF-κB Fans the Flames of Lung Carcinogenesis
by: Wong, Kwok-Kin, et al.
Published: (2014)

X-ray Crystallographic Study of Preferred Spacing by the NF-κB p50 Homodimer on κB DNA
by: Norman Zhu, et al.
Published: (2023-08-01)

UniPROBE: an online database of protein binding microarray data on protein–DNA interactions
by: Bulyk, Martha L., et al.
Published: (2012)

Targeting NF-κB Signaling for Multiple Myeloma
by: Ada Hang-Heng Wong, et al.
Published: (2020-08-01)

DNA binding polarity, dimerization, and ATPase ring remodeling in the CMG helicase of the eukaryotic replisome
by: Alessandro Costa, et al.
Published: (2014-08-01)

Hypoxia Induced NF-κB
by: Laura D’Ignazio, et al.
Published: (2016-03-01)

NF-κB in Hematological Malignancies
by: Véronique Imbert, et al.
Published: (2017-05-01)

Curated collection of yeast transcription factor DNA binding specificity data reveals novel structural and gene regulatory insights
by: Gordan, Raluca, et al.
Published: (2012)

Loss of ATRX promotes aggressive features of osteosarcoma with increased NF-κB signaling and integrin binding
by: Suzanne Bartholf DeWitt, et al.
Published: (2022-09-01)

NF-κB-inducing kinase is dispensable for activation of NF-κB in inflammatory settings but essential for lymphotoxin β receptor activation of NF-κB in primary human fibroblasts
by: Smith, C, et al.
Published: (2001)