Expression of prolyl-hydroxylases PHD-1, 2 and 3 and of the asparagine hydroxylase FIH in non-small cell lung cancer relates to an activated HIF pathway
The oxygen sensitive prolyl-hydroxylase domain enzymes (PHDs) and the asparagines hydroxylase (FIH, factor inhibiting HIF) regulate the transcriptional activity of HIFs. We assessed the expression of these enzymes in a series of 73 non-small cell lung carcinomas (NSCLC). A direct association of PHDs...
প্রধান লেখক: | Giatromanolaki, A, Koukourakis, M, Pezzella, F, Turley, H, Sivridis, E, Bouros, D, Bougioukas, G, Harris, A, Gatter, K |
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বিন্যাস: | Journal article |
ভাষা: | English |
প্রকাশিত: |
2008
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অনুরূপ উপাদানগুলি
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Expression of prolyl-hydroxylases PHD-1, 2 and 3 and of the asparagine hydroxylase FIH in non-small cell lung cancer relates to an activated HIF pathway.
অনুযায়ী: Giatromanolaki, A, অন্যান্য
প্রকাশিত: (2008) -
The use of dioxygen by HIF prolyl hydroxylase (PHD1).
অনুযায়ী: McNeill, L, অন্যান্য
প্রকাশিত: (2002) -
Hypoxia-inducible factor (HIF) asparagine hydroxylase is identical to factor inhibiting HIF (FIH) and is related to the cupin structural family.
অনুযায়ী: Hewitson, K, অন্যান্য
প্রকাশিত: (2002) -
Regulation of HIF: prolyl hydroxylases.
অনুযায়ী: Stolze, I, অন্যান্য
প্রকাশিত: (2006) -
Overexpression of the HIF hydroxylases PHD1, PHD2, PHD3 and FIH are individually and collectively unfavorable prognosticators for NSCLC survival.
অনুযায়ী: Sigve Andersen, অন্যান্য
প্রকাশিত: (2011-01-01)