Discovery of novel immunopharmacological ligands targeting the IL-17 inflammatory pathway

Interleukin 17 (IL-17) is a proinflammatory cytokine that acts as an immune checkpoint for several autoimmune diseases. Therapeutic neutralizing antibodies that target this cytokine have demonstrated clinical efficacy in psoriasis. However, biologics have limitations such as their high cost and thei...

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Bibliographic Details
Main Authors: Álvarez-Coiradas, E, Munteanu, CR, Díaz-Sáez, L, Pazos, A, Huber, KVM, Loza, MI, Domínguez, E
Format: Journal article
Language:English
Published: Elsevier 2020