Fluorescently labeled risedronate and related analogues: "magic linker" synthesis.
We report synthesis of the first fluorescently labeled conjugates of risedronate (1), using an epoxide linker strategy enabling conjugation of 1 via its pyridyl nitrogen with the label (carboxyfluorescein). Unlike prior approaches to create fluorescent bisphosphonate probes, the new linking chemistr...
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Bibliographic Details
Main Authors: |
Kashemirov, B,
Bala, J,
Chen, X,
Ebetino, F,
Xia, Z,
Russell, R,
Coxon, F,
Roelofs, A,
Rogers, M,
McKenna, C |
Format: | Journal article
|
Language: | English |
Published: |
2008
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