Fluorescently labeled risedronate and related analogues: "magic linker" synthesis.
We report synthesis of the first fluorescently labeled conjugates of risedronate (1), using an epoxide linker strategy enabling conjugation of 1 via its pyridyl nitrogen with the label (carboxyfluorescein). Unlike prior approaches to create fluorescent bisphosphonate probes, the new linking chemistr...
Main Authors: | Kashemirov, B, Bala, J, Chen, X, Ebetino, F, Xia, Z, Russell, R, Coxon, F, Roelofs, A, Rogers, M, McKenna, C |
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Format: | Journal article |
Language: | English |
Published: |
2008
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