Cell-specific loss of SNAP25 from cortical projection
neurons allows normal development but causes
subsequent neurodegeneration

Cell-specific loss of SNAP25 from cortical projection neurons allows normal development but causes subsequent neurodegeneration

Synaptosomal associated protein 25 kDa (SNAP25) is an essential component of the SNARE complex regulating synaptic vesicle fusion. SNAP25 deficiency has been implicated in a variety of cognitive disorders. We ablated SNAP25 from selected neuronal populations by generating a transgenic mouse (B6-Snap...

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Bibliographic Details
Main Authors:	Hoerder-Suabedissen, A, Korrell, KV, Hayashi, S, Jeans, A, Ramirez, DMO, Grant, E, Christian, HC, Kavalali, ET, Wilson, MC, Molnár, Z
Format:	Journal article
Language:	English
Published:	Oxford University Press 2018

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