Transcriptional Gene Silencing: An Epigenetic Myostatin Blockade Strategy

Transcriptional Gene Silencing: An Epigenetic Myostatin Blockade Strategy

Detalhes bibliográficos
Main Authors:	Roberts, T, McClorey, C, Andaloussi, S, Morris, K, Wood, M
Formato:	Journal article
Publicado em:	2011

Registos relacionados

Small RNA-Mediated Epigenetic Myostatin Silencing.
Por: Roberts, T, et al.
Publicado em: (2012)

LEPIGENETIC MYOSTATIN BLOCKADE
Por: Roberts, T, et al.
Publicado em: (2011)

Epigenetic and genetic mechanisms through which Myostatin regulates muscle wasting
Por: Lua, Gavian Bing Jia
Publicado em: (2016)

An epigenetic blockade of cognitive functions in the neurodegenerating brain
Por: Rei, Damien, et al.
Publicado em: (2015)

Therapeutic gene silencing strategies for polyglutamine disorders.
Por: Scholefield, J, et al.
Publicado em: (2010)

Epigenetic silencing of CYP24 in the tumor microenvironment
Por: Johnson, C.S., et al.
Publicado em: (2010)

Novel RNA-based strategies for therapeutic gene silencing.
Por: Sibley, C, et al.
Publicado em: (2010)

Downregulation of myostatin pathway in neuromuscular diseases may explain challenges of anti-myostatin therapeutic approaches
Por: Mariot, V, et al.
Publicado em: (2017)

Regulation of muscle metabolism by myostatin
Por: Zhang, Chen
Publicado em: (2012)

Treatment of sarcopenia by antagonists of myostatin
Por: Anissa Anindya Widjaja
Publicado em: (2013)

Myostatin-null mice exhibit delayed skin wound healing through the blockade of transforming growth factor- β signaling by decorin
Por: Zhang, Chen, et al.
Publicado em: (2013)

Convergent transcription induces transcriptional gene silencing in fission yeast and mammalian cells.
Por: Gullerova, M, et al.
Publicado em: (2012)

Profile of circadianly regulated metabolic genes in dystrophic heart
Por: Betts, C, et al.
Publicado em: (2018)

Germline epigenetic silencing of the tumor suppressor gene PTPRJ in early-onset familial colorectal cancer.
Por: Venkatachalam, R, et al.
Publicado em: (2010)

Splice-switching therapy for spinal muscular atrophy.
Por: Meijboom, K, et al.
Publicado em: (2017)

Myostatin polymorphism in Bali cattle and the gaur
Por: Radzuan, Khairun Nadwa
Publicado em: (2016)

[Withdrawn] Regulation of insulin resistance by myostatin
Por: Sabeera Bonala
Publicado em: (2013)

Advancing the potential of peptide-PMO compounds in exon skipping therapy for DMD
Por: Godfrey, C, et al.
Publicado em: (2012)

Allele-specific RNA interference to target a model of slow-channel congenital myasthenic syndrome
Por: McClorey, G, et al.
Publicado em: (2008)

Expression analysis in multiple muscle groups and serum reveals complexity in the microRNA transcriptome of the mdx mouse with implications for therapy.
Por: Roberts, T, et al.
Publicado em: (2012)

Epigenetic silencing of RASSF1A promotes tumourigenesis via alternative transcript expression, SFK activation and exosome secretion
Por: Vlahov, N
Publicado em: (2015)

Cell-penetrating peptides to enhance delivery of Oligonucleotide-based therapeutics
Por: McClorey, G, et al.
Publicado em: (2018)

Combined epigenetic and metabolic treatments overcome differentiation blockade in acute myeloid leukemia
Por: Zee, BM, et al.
Publicado em: (2021)

Design and application of bispecific splice-switching oligonucleotides.
Por: Bestas, B, et al.
Publicado em: (2014)

Characterisation of ant-1 as an inhibitor of myostatin activity.
Por: Irfana Begum Ikbal.
Publicado em: (2011)

Role of Myostatin in oxidative stress in skeletal muscle
Por: Sandhya Sriram
Publicado em: (2013)

The regulation of cancer cachexia and colorectal carcinogenesis by myostatin
Por: Wijesoma, Isuru Wijerupage
Publicado em: (2017)

Transcriptional and epigenetic mechanisms of promiscuous gene expression by thymic epithelial cells
Por: Dhalla, F
Publicado em: (2019)

Therapeutic gene silencing in the nervous system.
Por: Wood, M, et al.
Publicado em: (2003)

Transcription of antisense RNA leading to gene silencing and methylation as a novel cause of human genetic disease.
Por: Tufarelli, C, et al.
Publicado em: (2003)

Transcriptional and epigenetic fluctuations in single cells
Por: Klemm, Sandy Lee
Publicado em: (2015)

Screening and characterization of potential small molecule antagonists of myostatin.
Por: Lee, Rachel Hui Min.
Publicado em: (2012)

Epigenetic silencing of HNF1A associates with changes in the composition of the human plasma N-glycome.
Por: Zoldoš, V, et al.
Publicado em: (2012)

Histone deacetylation promotes transcriptional silencing at facultative heterochromatin
Por: Watts, B, et al.
Publicado em: (2018)

Transcriptional and epigenetic mechanisms underlying astrocyte identity
Por: Pavlou, M, et al.
Publicado em: (2018)

Gene silencing through RNA interference and antisense strategies in the lung
Por: Griesenbach, U, et al.
Publicado em: (2003)

Epigenetic and post-transcriptional regulation of gene expression in pluripotent stem cells, differentiation and metastasis
Por: Cheng, Wu Albert
Publicado em: (2014)

How transcriptional and epigenetic programmes are played out on an individual mammalian gene cluster during lineage commitment and differentiation.
Por: Higgs, D, et al.
Publicado em: (2006)

[Retracted] Myostatin is a novel tumoral factor that induces cancer cachexia
Por: Lokireddy, Sudarsanareddy, et al.
Publicado em: (2013)

Epigenetic blockade of neoplastic transformation by bromodomain and extra-terminal (BET) domain protein inhibitor JQ-1
Por: Zhang, C, et al.
Publicado em: (2016)