A Novel Role for Endothelial Tetrahydrobiopterin in Mitochondrial Redox Balance
The redox co-factor tetrahydrobiopterin (BH4) regulates nitric oxide (NO) and reactive oxygen species (ROS) production by endothelial NOS (eNOS) and is an important redox-dependent signalling molecule in the endothelium. Loss of endothelial BH4 is observed in cardiovascular disease (CVD) states and...
| Main Authors: | , , , , , , , , |
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| Format: | Journal article |
| Published: |
Elsevier
2017
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