A Novel Role for Endothelial Tetrahydrobiopterin in Mitochondrial Redox Balance

A Novel Role for Endothelial Tetrahydrobiopterin in Mitochondrial Redox Balance

The redox co-factor tetrahydrobiopterin (BH4) regulates nitric oxide (NO) and reactive oxygen species (ROS) production by endothelial NOS (eNOS) and is an important redox-dependent signalling molecule in the endothelium. Loss of endothelial BH4 is observed in cardiovascular disease (CVD) states and...

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Bibliografische gegevens
Hoofdauteurs:	Bailey, J, Shaw, A, Fischer, R, Ryan, B, Kessler, B, McCullagh, J, Wade-Martins, R, Channon, K, Crabtree, M
Formaat:	Journal article
Gepubliceerd in:	Elsevier 2017

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