A whole genome association study of neuroticism using DNA pooling.
We describe a multistage approach to identify single nucleotide polymorphisms (SNPs) associated with neuroticism, a personality trait that shares genetic determinants with major depression and anxiety disorders. Whole genome association with 452 574 SNPs was performed on DNA pools from approximately...
Main Authors: | Shifman, S, Bhomra, A, Smiley, S, Wray, N, James, MR, Martin, N, Hettema, J, An, S, Neale, M, van den Oord, E, Kendler, K, Chen, X, Boomsma, D, Middeldorp, C, Hottenga, J, Slagboom, P, Flint, J |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2008
|
Similar Items
-
Human-mouse quantitative trait locus concordance and the dissection of a human neuroticism locus.
by: Fullerton, J, et al.
Published: (2008) -
The genetic basis of neuroticism.
by: Flint, J
Published: (2004) -
Is there an association between NPY and neuroticism?
by: Cotton, C, et al.
Published: (2009) -
Are there sex differences in the association between the 5HTT gene and neuroticism? A meta-analysis
by: Munafo, MR, et al.
Published: (2004) -
The serotonin transporter length polymorphism, neuroticism, and depression: a comprehensive assessment of association.
by: Willis-Owen, SA, et al.
Published: (2005)