Deficient RPE mitochondrial energetics leads to subretinal fibrosis in age-related neovascular macular degeneration

Subretinal fibrosis permanently impairs the vision of patients with neovascular age-related macular degeneration. Despite emerging evidence revealing the association between disturbed metabolism in retinal pigment epithelium (RPE) and subretinal fibrosis, the underlying mechanism remains unclear. In...

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Detalhes bibliográficos
Main Authors: Ma, X, Wu, W, Hara, M, Zhou, J, Panzarin, C, Schafer, CM, Griffin, CT, Cai, J, Ma, J, Takahashi, Y
Formato: Journal article
Idioma:English
Publicado em: Nature Research 2024