Bilayer deformation by the Kv channel voltage sensor domain revealed by self-assembly simulations.

Coarse-grained molecular dynamics simulations are used to explore the interaction with a phospholipid bilayer of the voltage sensor (VS) domain and the S4 helix from the archaebacterial voltage-gated potassium (Kv) channel KvAP. Multiple 2-mus self-assembly simulations reveal that the isolated S4 he...

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Détails bibliographiques
Auteurs principaux: Bond, P, Sansom, MS
Format: Journal article
Langue:English
Publié: 2007