Bilayer deformation by the Kv channel voltage sensor domain revealed by self-assembly simulations.
Coarse-grained molecular dynamics simulations are used to explore the interaction with a phospholipid bilayer of the voltage sensor (VS) domain and the S4 helix from the archaebacterial voltage-gated potassium (Kv) channel KvAP. Multiple 2-mus self-assembly simulations reveal that the isolated S4 he...
Main Authors: | Bond, P, Sansom, MS |
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Format: | Journal article |
Language: | English |
Published: |
2007
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