Pharmacokinetic and pharmacodynamic considerations in antimalarial dose optimization.

Antimalarial drugs have usually been first deployed in areas of malaria endemicity at doses which were too low, particularly for high-risk groups such as young children and pregnant women. This may accelerate the emergence and spread of resistance, thereby shortening the useful life of the drug, but...

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Autor principal: White, N
Format: Journal article
Idioma:English
Publicat: 2013