Pharmacokinetic and pharmacodynamic considerations in antimalarial dose optimization.
Antimalarial drugs have usually been first deployed in areas of malaria endemicity at doses which were too low, particularly for high-risk groups such as young children and pregnant women. This may accelerate the emergence and spread of resistance, thereby shortening the useful life of the drug, but...
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| Médium: | Journal article |
| Jazyk: | English |
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2013
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