Influenza A vaccine based on the extracellular domain of M2: weak protection mediated via antibody-dependent NK cell activity.
Vaccination of mice with a peptide corresponding to the extracellular part of M2 protein coupled to the immunodominant domain of hepatitis B core can protect mice from a lethal challenge with influenza A virus. As the extracellular part of M2 protein is highly conserved in all known human influenza...
المؤلفون الرئيسيون: | Jegerlehner, A, Schmitz, N, Storni, T, Bachmann, M |
---|---|
التنسيق: | Journal article |
اللغة: | English |
منشور في: |
2004
|
مواد مشابهة
-
Universal vaccine against influenza virus: linking TLR signaling to anti-viral protection.
حسب: Schmitz, N, وآخرون
منشور في: (2012) -
Virus-like particles as carriers for T-cell epitopes: limited inhibition of T-cell priming by carrier-specific antibodies.
حسب: Ruedl, C, وآخرون
منشور في: (2005) -
A universal Influenza A vaccine based on M2 mediates complete protection from lethal infection in mice
حسب: Schmitz, N, وآخرون
منشور في: (2007) -
Critical role for activation of antigen-presenting cells in priming of cytotoxic T cell responses after vaccination with virus-like particles.
حسب: Storni, T, وآخرون
منشور في: (2002) -
Bacterially produced recombinant influenza vaccines based on virus-like particles
حسب: Jegerlehner, A, وآخرون
منشور في: (2013)