Influenza A vaccine based on the extracellular domain of M2: weak protection mediated via antibody-dependent NK cell activity.
Vaccination of mice with a peptide corresponding to the extracellular part of M2 protein coupled to the immunodominant domain of hepatitis B core can protect mice from a lethal challenge with influenza A virus. As the extracellular part of M2 protein is highly conserved in all known human influenza...
Hlavní autoři: | Jegerlehner, A, Schmitz, N, Storni, T, Bachmann, M |
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Médium: | Journal article |
Jazyk: | English |
Vydáno: |
2004
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