Pharmacokinetics of oral doxycycline during combination treatment of severe falciparum malaria.
The pharmacokinetics of oral doxycycline administered at 200 mg every 24 h were investigated in 17 patients recovering from severe Plasmodium falciparum malaria. The data suggest that the doses of doxycycline currently recommended (circa 3.5 mg/kg of body weight daily) may not be optimal.
Bibliografiske detaljer
Main Authors: |
Newton, P,
Chaulet, J,
Brockman, A,
Chierakul, W,
Dondorp, A,
Ruangveerayuth, R,
Looareesuwan, S,
Mounier, C,
White, N |
Format: | Journal article
|
Sprog: | English |
Udgivet: |
2005
|