Pharmacokinetics of oral doxycycline during combination treatment of severe falciparum malaria.

The pharmacokinetics of oral doxycycline administered at 200 mg every 24 h were investigated in 17 patients recovering from severe Plasmodium falciparum malaria. The data suggest that the doses of doxycycline currently recommended (circa 3.5 mg/kg of body weight daily) may not be optimal.

מידע ביבליוגרפי
Main Authors: Newton, P, Chaulet, J, Brockman, A, Chierakul, W, Dondorp, A, Ruangveerayuth, R, Looareesuwan, S, Mounier, C, White, N
פורמט: Journal article
שפה:English
יצא לאור: 2005
תיאור
סיכום:The pharmacokinetics of oral doxycycline administered at 200 mg every 24 h were investigated in 17 patients recovering from severe Plasmodium falciparum malaria. The data suggest that the doses of doxycycline currently recommended (circa 3.5 mg/kg of body weight daily) may not be optimal.