Role of delta-like 4 in solid tumours and response to radiation therapy

<p>Delta-like ligand 4 (DLL4) is a ligand for the Notch family of receptors. DLL4 is an important regulator of angiogenesis and DLL4 blockade promotes non-productive angiogenesis and delays tumour growth. The aim of this thesis was to investigate the effects of anti-DLL4 therapy in solid tumou...

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Bibliographic Details
Main Author: Bham, S
Other Authors: Harris, A
Format: Thesis
Language:English
Published: 2013
Subjects: