Genome-wide association and functional studies identify the DOT1L gene to be involved in cartilage thickness and hip osteoarthritis.

Genome-wide association and functional studies identify the DOT1L gene to be involved in cartilage thickness and hip osteoarthritis.

Hip osteoarthritis (HOA) is one of the most disabling and common joint disorders with a large genetic component that is, however, still ill-defined. To date, genome-wide association studies (GWAS) in osteoarthritis (OA) and specifically in HOA have yielded only few loci, which is partly explained by...

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Dettagli Bibliografici
Autori principali:	Betancourt, C, Cailotto, F, Kerkhof, H, Cornelis, F, Doherty, SA, Hart, D, Hofman, A, Luyten, F, Maciewicz, R, Mangino, M, Metrustry, S, Muir, K, Peters, M, Rivadeneira, F, Wheeler, M, Zhang, W, Arden, N, Spector, T, Uitterlinden, A, Doherty, M, Lories, R, Valdes, A, van Meurs, J
Natura:	Journal article
Lingua:	English
Pubblicazione:	2012

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