TLR signaling in human antigen-presenting cells regulates MR1-dependent activation of MAIT cells

TLR signaling in human antigen-presenting cells regulates MR1-dependent activation of MAIT cells

Mucosal-associated invariant T (MAIT) cells are an abundant innate-like T lymphocyte population that are enriched in liver and mucosal tissues. They are restricted by MR1, which presents antigens derived from a metabolic precursor of riboflavin synthesis, a pathway present in many microbial species,...

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Bibliographic Details
Main Authors:	Ussher, J, van Wilgenburg, B, Hannaway, R, Ruustal, K, Phalora, P, Kurioka, A, Hansen, T, Willberg, C, Phillips, R, Klenerman, P
Format:	Journal article
Language:	English
Published:	Wiley 2016

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