Stochastic modelling and simulation in cell biology

Stochastic modelling and simulation in cell biology

<p>Modelling and simulation are essential to modern research in cell biology. This thesis follows a journey starting from the construction of new stochastic methods for discrete biochemical systems to using them to simulate a population of interacting haematopoietic stem cell lineages.</p&g...

Fuld beskrivelse

Bibliografiske detaljer
Main Authors:	Szekely, T, Tamas Szekely
Andre forfattere:	Burrage, K
Format:	Thesis
Sprog:	English
Udgivet:	2014
Fag:	Probability theory and stochastic processes Biology and other natural sciences (mathematics) Computational biochemistry Biology (medical sciences) Cell Biology (see also Plant sciences) Chemical kinetics Biology Computer science (mathematics) Mathematical biology Stem cells (clinical sciences)

Lignende værker

Structure-function studies of fibronectin domains in the human endometrium
af: Mok, M, et al.
Udgivet: (2008)

Computational biology and the limits of shared vision
af: Carusi, A
Udgivet: (2009)

The role and regulation of Asterless in the centrosome cycle
af: Novak, ZA
Udgivet: (2014)

Towards understanding the mechanism of cohesin loading
af: Dixon, SE
Udgivet: (2013)

Functions of conserved centriole proteins in African trypanosomes
af: Scheumann, N
Udgivet: (2012)

E2F7: a member of the E2F family with a novel mechanism of transcriptional repression
af: Kesoglidou, PX
Udgivet: (2012)

Forum for scientific method in biology: transcript
af: Carusi, A, et al.
Udgivet: (2009)

Aspects to T-cell phenotype during infection with HIV, CMV and Hepatitis C virus
af: Northfield, J
Udgivet: (2008)

The role of protein kinase C in platelet activation
af: Unsworth, AJ
Udgivet: (2012)

Vertex model approaches to epithelial tissues in developmental systems
af: Smith, A
Udgivet: (2012)

Regulation of E2F-1 by methylation and NEDDylation
af: Loftus, S, et al.
Udgivet: (2012)

Characterisation of AEBP2: a polycomb repressive complex 2 component
af: Grijzenhout, A
Udgivet: (2013)

Functional organisation of the Hrd1 ubiquitin ligase complex and its role in ERAD
af: Schulz, J
Udgivet: (2013)

Determining the mechanism of pathogenesis of mucolipidosis type IV and related lysosomal storage disorders for development of novel therapies
af: Peterneva, K
Udgivet: (2014)

Syncrip regulates mRNA localisation and translation at the drosophila neuromuscular junction
af: Halstead, J
Udgivet: (2013)

Mathematical models of cranial neural crest cell migration
af: Dyson, L
Udgivet: (2013)

Pathways for glycoprotein degradation in mammalian cells
af: Kukushkin, N, et al.
Udgivet: (2011)

Human orthologues of Saccharomyces cerevisiae Trf4/5 non-canonical poly(A) polymerases
af: Gibson, K
Udgivet: (2011)

Functional analysis of cancer/testis antigens in human cancer
af: Pagotto, A
Udgivet: (2013)

Assessing the role of ADAM10 in Trastuzumab treatment and resistance
af: Feldinger, K
Udgivet: (2012)

Identification and characterisation of homologous recombination genes in Schizosaccharomyces pombe
af: Moss, J
Udgivet: (2011)

Cell stress response and hypoxia in breast cancer
af: Milani, M, et al.
Udgivet: (2011)

Nitric oxide: a chemical effector of pathogenesis in magnaporthe oryzae
af: Johnson, J
Udgivet: (2011)

Targeting cell adhesion as a method of sensitising metastatic tumour cells to TRAIL-induced apoptosis
af: Phipps, L
Udgivet: (2011)

Effective design of marine reserves: incorporating alongshore currents, size structure, and uncertainty
af: Reimer, J
Udgivet: (2013)

Stochastic modelling of the cell cycle
af: He, E
Udgivet: (2012)

Recent modelling frameworks for systems of interacting particles
af: Franz, B
Udgivet: (2014)

Investigating the function of Drosophila MAPs Msd1 and dTD-60 in mitotic spindle assembly
af: Duncan, T
Udgivet: (2011)

Design, implementation and experimental validation of a network-based model to predict mitotic microtubule regulating proteins
af: Khan, FF
Udgivet: (2013)

Deconstructing the trypanosome cytoskeleton: from structures to functions via components and complexes.
af: Portman, N
Udgivet: (2011)

Tet2 and relevant potential intervention in cancer
af: Zauri, M
Udgivet: (2014)

Induced regulatory T cells in transplantation tolerance
af: Chen, Y
Udgivet: (2010)

Towards a computational model of the colonic crypt with a realistic, deformable geometry
af: Dunn, S
Udgivet: (2011)

Cell fate mechanisms in colorectal cancer
af: Kay, SK
Udgivet: (2014)

Heterogeneity of tumour response to hypoxia: carbonic anhydrase IX induction defines a subpopulation of hypoxic cells with stem cell properties and drug resistance
af: Ledaki, I
Udgivet: (2013)

The evolution of eukaryotic cilia
af: Hodges, M, et al.
Udgivet: (2011)

Confocal single-molecule fluorescence as a tool for investigating biomolecular dynamics in vitro and in vivo
af: Torella, J, et al.
Udgivet: (2011)

The mechanism of Nov (CCN3) function in haematopoiesis
af: Guo, Y
Udgivet: (2012)

Mathematical modelling of Centrosomin incorporation in Drosophila centrosomes
af: Bakshi, S
Udgivet: (2013)

Mechanisms of induction and modulation of the pro-inflammatory cytokine interleukin-1beta
af: Yip, RHN
Udgivet: (2012)