Structure of the Helicobacter pylori CagA oncoprotein bound to the human tumor suppressor ASPP2.
The Cytotoxin associated gene A (CagA) protein of Helicobacter pylori is associated with increased virulence and risk of cancer. Recent proteomic studies have demonstrated an association of CagA with the human tumor suppressor Apoptosis-stimulating Protein of p53-2 (ASPP2). We present here a genetic...
المؤلفون الرئيسيون: | Nešić, D, Buti, L, Lu, X, Stebbins, C |
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التنسيق: | Journal article |
اللغة: | English |
منشور في: |
2014
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مواد مشابهة
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Helicobacter pylori cytotoxin-associated gene A (CagA) subverts the apoptosis-stimulating protein of p53 (ASPP2) tumor suppressor pathway of the host
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Differential Mechanisms for SHP2 Binding and Activation Are Exploited by Geographically Distinct Helicobacter pylori CagA Oncoproteins
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