Structure of the Helicobacter pylori CagA oncoprotein bound to the human tumor suppressor ASPP2.

The Cytotoxin associated gene A (CagA) protein of Helicobacter pylori is associated with increased virulence and risk of cancer. Recent proteomic studies have demonstrated an association of CagA with the human tumor suppressor Apoptosis-stimulating Protein of p53-2 (ASPP2). We present here a genetic...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Nešić, D, Buti, L, Lu, X, Stebbins, C
التنسيق: Journal article
اللغة:English
منشور في: 2014