Structure of the Helicobacter pylori CagA oncoprotein bound to the human tumor suppressor ASPP2.

The Cytotoxin associated gene A (CagA) protein of Helicobacter pylori is associated with increased virulence and risk of cancer. Recent proteomic studies have demonstrated an association of CagA with the human tumor suppressor Apoptosis-stimulating Protein of p53-2 (ASPP2). We present here a genetic...

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Hlavní autoři: Nešić, D, Buti, L, Lu, X, Stebbins, C
Médium: Journal article
Jazyk:English
Vydáno: 2014