A concise synthesis of the octalactins.
The total synthesis of octalactins A and B has been achieved in 15 steps (longest linear sequence) and 10% overall yield from commercially available materials. Key steps include the Paterson-Aldol reaction for the rapid assembly of the carbonate 46, methylenation of 46 and subsequent Claisen rearran...
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| Hlavní autoři: |
O'Sullivan, P,
Buhr, W,
Fuhry, M,
Harrison, JR,
Davies, J,
Feeder, N,
Marshall, DR,
Burton, J,
Holmes, AB |
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| Médium: | Journal article
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| Jazyk: | English |
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| Vydáno: |
2004
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