A concise synthesis of the octalactins.
The total synthesis of octalactins A and B has been achieved in 15 steps (longest linear sequence) and 10% overall yield from commercially available materials. Key steps include the Paterson-Aldol reaction for the rapid assembly of the carbonate 46, methylenation of 46 and subsequent Claisen rearran...
Main Authors: | , , , , , , , , |
---|---|
格式: | Journal article |
語言: | English |
出版: |
2004
|