Host immunity and the assessment of emerging artemisinin resistance in a multinational cohort
38 Artemisinin-resistant falciparum malaria, defined by a slow-clearance phenotype and the presence of kelch13 mutants, has emerged in the Greater Mekong Subregion. Naturally-acquired immunity to malaria clears parasites independently of antimalarial drugs. We hypothesise that between- and within-po...
Main Authors: | Ataide, R, Ashley, E, Powell, R, Chan, J, Malloy, M, O'Flaherty, K, Takashima, E, Langer, C, Tsuboi, T, Dondorp, A, Day, N, Dhorda, M, Fairhurst, R, Lim, P, Amaratunga, C, Pukrittayakamee, S, Hien, T, Htut, Y, Mayxay, M, Faiz, M, Beeson, J, Nosten, F, Simpson, J, White, N, Fowkes, F |
---|---|
Format: | Journal article |
Published: |
National Academy of Sciences
2017
|
Similar Items
-
The contribution of functional antimalarial immunity to measures of parasite clearance in therapeutic efficacy studies of artemisinin derivatives
by: O'Flaherty, K, et al.
Published: (2019) -
Comparison of antibody responses and parasite clearance in artemisinin therapeutic efficacy studies in Democratic Republic of Congo and Asia
by: Cutts, JC, et al.
Published: (2022) -
Anti-gametocyte antigen humoral immunity and gametocytemia during treatment of uncomplicated falciparum malaria: a multi-national study
by: O'Flaherty, K, et al.
Published: (2022) -
Population transcriptomics of human malaria parasites reveals the mechanism of artemisinin resistance
by: Mok, S., et al.
Published: (2016) -
Triple artemisinin-based combination therapies for malaria – a new paradigm?
by: van der Pluijm, RW, et al.
Published: (2020)