Direct whole-genome deep-sequencing of human respiratory syncytial virus A and B from Vietnamese children identifies distinct patterns of inter- and intra-host evolution

Human respiratory syncytial virus (RSV) is the major cause of lower respiratory tract infections in children < 2 years of age. Little is known about RSV intra-host genetic diversity over the course of infection or about the immune pressures that drive RSV molecular evolution. We performed who...

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Detalhes bibliográficos
Main Authors: Do, LAH, Wilm, A, Van Doorn, HR, Lam, HM, Sim, S, Sukumaran, R, Tran, AT, Nguyen, BH, Tran, TTL, Tran, QH, Vo, QB, Dac, NAT, Trinh, HN, Nguyen, TTH, Binh, BTL, Le, K, Nguyen, MT, Thai, QT, Vo, TV, Ngo, NQM, Dang, TKH, Cao, NH, Tran, TV, Ho, LV, Farrar, J, Jong, MD, Chen, S, Nagarajan, N, Bryant, JE, Hibberd, ML
Formato: Journal article
Idioma:English
Publicado em: Microbiology Society 2015