ADP-ribosylation: new facets of an ancient modification
Rapid response to environmental changes is achieved by uni- and multicellular organisms through a series of molecular events, often involving modification of macromolecules, including proteins, nucleic acids and lipids. Amongst these, ADP-ribosylation is of emerging interest because of its ability t...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
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Wiley
2017
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| _version_ | 1826306154881351680 |
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| author | Palazzo, L Mikoč, A Ahel, I |
| author_facet | Palazzo, L Mikoč, A Ahel, I |
| author_sort | Palazzo, L |
| collection | OXFORD |
| description | Rapid response to environmental changes is achieved by uni- and multicellular organisms through a series of molecular events, often involving modification of macromolecules, including proteins, nucleic acids and lipids. Amongst these, ADP-ribosylation is of emerging interest because of its ability to modify different macromolecules in the cells, and its association with many key biological processes, such as DNA-damage repair, DNA replication, transcription, cell division, signal transduction, stress and infection responses, microbial pathogenicity and aging. In this review, we provide an update on novel pathways and mechanisms regulated by ADPribosylation in organisms coming from all kingdoms of life. |
| first_indexed | 2024-03-07T06:43:38Z |
| format | Journal article |
| id | oxford-uuid:fa24d231-3b3f-415a-a002-e9ab50d3c310 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T06:43:38Z |
| publishDate | 2017 |
| publisher | Wiley |
| record_format | dspace |
| spelling | oxford-uuid:fa24d231-3b3f-415a-a002-e9ab50d3c3102022-03-27T13:03:23ZADP-ribosylation: new facets of an ancient modificationJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:fa24d231-3b3f-415a-a002-e9ab50d3c310EnglishSymplectic Elements at OxfordWiley2017Palazzo, LMikoč, AAhel, IRapid response to environmental changes is achieved by uni- and multicellular organisms through a series of molecular events, often involving modification of macromolecules, including proteins, nucleic acids and lipids. Amongst these, ADP-ribosylation is of emerging interest because of its ability to modify different macromolecules in the cells, and its association with many key biological processes, such as DNA-damage repair, DNA replication, transcription, cell division, signal transduction, stress and infection responses, microbial pathogenicity and aging. In this review, we provide an update on novel pathways and mechanisms regulated by ADPribosylation in organisms coming from all kingdoms of life. |
| spellingShingle | Palazzo, L Mikoč, A Ahel, I ADP-ribosylation: new facets of an ancient modification |
| title | ADP-ribosylation: new facets of an ancient modification |
| title_full | ADP-ribosylation: new facets of an ancient modification |
| title_fullStr | ADP-ribosylation: new facets of an ancient modification |
| title_full_unstemmed | ADP-ribosylation: new facets of an ancient modification |
| title_short | ADP-ribosylation: new facets of an ancient modification |
| title_sort | adp ribosylation new facets of an ancient modification |
| work_keys_str_mv | AT palazzol adpribosylationnewfacetsofanancientmodification AT mikoca adpribosylationnewfacetsofanancientmodification AT aheli adpribosylationnewfacetsofanancientmodification |