MAIT cells are activated during human viral infections

MAIT cells are activated during human viral infections

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Mucosal Associated Invariant T (MAIT) cells are abundant in humans and recognise bacterial ligands. Here we demonstrate that MAIT cells are also activated during human viral infections in vivo. MAIT cells activation was observed during infection with Dengue virus, Hepatitis C virus, and Influenza Vi...

Bibliografski detalji
Glavni autori:	Van Wilgenburg, B, Klenerman, P, Willberg, C, Kurioka, A, Ramamurthy, N, Leng, T, De Lara, C, Scherwitzl, I, Hutchinson, E, Kulicke, C, Cole, S, Vasanawathana, S, Limpitikul, W, Malasit, P, Young, D, Denney, L, Moore, M, Fabris, P, Giordani, M, Oo, Y, Laidlaw, S, Dustin, L, Ho, L, Thompson, F, Mongkolsapaya, J, Screaton, G
Format:	Journal article
Izdano:	Nature Publishing Group 2016

Slični predmeti

MAIT cells are activated during human viral infections.
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MAIT cells induce proinflammatory cytokine production in monocytes through the secretion of granzymes A and K
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MAIT cells are licensed through granzyme exchange to kill bacterially sensitized targets.
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MR1-dependent activation of intrahepatic MAIT cells by bacterially exposed biliary epithelial cells and liver B cells
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