Functional analysis of the ATM-p53-p21 pathway in the LRF CLL4 trial: blockade at the level of p21 is associated with short response duration.

Functional analysis of the ATM-p53-p21 pathway in the LRF CLL4 trial: blockade at the level of p21 is associated with short response duration.

PURPOSE: This study sought to establish whether functional analysis of the ATM-p53-p21 pathway adds to the information provided by currently available prognostic factors in patients with chronic lymphocytic leukemia (CLL) requiring frontline chemotherapy. EXPERIMENTAL DESIGN: Cryopreserved blood mon...

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Bibliographic Details
Main Authors: Lin, K, Adamson, J, Johnson, G, Carter, A, Oates, M, Wade, R, Richards, S, Gonzalez, D, Matutes, E, Dearden, C, Oscier, D, Catovsky, D, Pettitt, A
Format: Journal article
Language:English
Published: 2012

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