MYH biallelic mutation can inactivate the two genetic pathways of colorectal cancer by APC or MLH1 transversions.

MYH associated polyposis is a hereditary syndrome responsible for early colorectal cancer with a distinct genetic pathway from the Familial Adenomatous Polyposis or the Hereditary Non Polyposis Colorectal Cancer syndrome. We have studied a family with three members bearing a biallelic mutation in MY...

সম্পূর্ণ বিবরণ

গ্রন্থ-পঞ্জীর বিবরন
প্রধান লেখক: Lefevre, J, Colas, C, Coulet, F, Bonilla, C, Mourra, N, Flejou, J, Tiret, E, Bodmer, W, Soubrier, F, Parc, Y
বিন্যাস: Journal article
ভাষা:English
প্রকাশিত: 2010