MYH biallelic mutation can inactivate the two genetic pathways of colorectal cancer by APC or MLH1 transversions.

類似資料

• Characterization of somatic mutations of colorectal tumor in a patient with concurrent APC and MLH1 germline mutations
  著者:: Yunsheng Cheng, 等
  出版事項: (2023-11-01)
• Investigation of pathogenic mechanisms in multiple colorectal adenoma patients without germline APC or MYH/MUTYH mutations.
  著者:: Thirlwell, C, 等
  出版事項: (2007)
• Myh deficiency enhances intestinal tumorigenesis in multiple intestinal neoplasia (ApcMin/+) mice.
  著者:: Sieber, O, 等
  出版事項: (2004)
• Mechanisms of inactivation of mismatch repair genes in human colorectal cancer cell lines: the predominant role of hMLH1.
  著者:: Wheeler, J, 等
  出版事項: (1999)
• Role of rare variants in undetermined multiple adenomatous polyposis and early-onset colorectal cancer.
  著者:: Lefevre, J, 等
  出版事項: (2012)