Clinical outcomes and costs due to Staphylococcus aureus bacteremia among patients receiving long-term hemodialysis.

OBJECTIVE: To examine the clinical outcomes and costs associated with Staphylococcus aureus bacteremia among hemodialysis-dependent patients. DESIGN: Prospectively identified cohort study. SETTING: A tertiary-care university medical center in North Carolina. PATIENTS: Two hundred ten hemodialysis-d...

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Main Authors: Engemann, J, Friedman, J, Reed, S, Griffiths, R, Szczech, L, Kaye, K, Stryjewski, M, Reller, L, Schulman, K, Corey, G, Fowler, V
Format: Journal article
Language:English
Published: 2005
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author Engemann, J
Friedman, J
Reed, S
Griffiths, R
Szczech, L
Kaye, K
Stryjewski, M
Reller, L
Schulman, K
Corey, G
Fowler, V
author_facet Engemann, J
Friedman, J
Reed, S
Griffiths, R
Szczech, L
Kaye, K
Stryjewski, M
Reller, L
Schulman, K
Corey, G
Fowler, V
author_sort Engemann, J
collection OXFORD
description OBJECTIVE: To examine the clinical outcomes and costs associated with Staphylococcus aureus bacteremia among hemodialysis-dependent patients. DESIGN: Prospectively identified cohort study. SETTING: A tertiary-care university medical center in North Carolina. PATIENTS: Two hundred ten hemodialysis-dependent adults with end-stage renal disease hospitalized with S. aureus bacteremia. RESULTS: The majority of the patients (117; 55.7%) underwent dialysis via tunneled catheters, and 29.5% (62) underwent dialysis via synthetic arteriovenous fistulas. Vascular access was the suspected source of bacteremia in 185 patients (88.1%). Complications occurred in 31.0% (65), and the overall 12-week mortality rate was 19.0% (40). The mean cost of treating S. aureus bacteremia, including readmissions and outpatient costs, was $24,034 per episode. The mean initial hospitalization cost was significantly greater for patients with complicated versus uncomplicated S. aureus bacteremia ($32,462 vs $17,011; P = .002). CONCLUSION: Interventions to decrease the rate of S. aureus bacteremia are needed in this high-risk, hemodialysis-dependent population.
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spelling oxford-uuid:fa5c89cd-0e12-4608-87b3-36e705c9f7802022-03-27T13:05:08ZClinical outcomes and costs due to Staphylococcus aureus bacteremia among patients receiving long-term hemodialysis.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:fa5c89cd-0e12-4608-87b3-36e705c9f780EnglishSymplectic Elements at Oxford2005Engemann, JFriedman, JReed, SGriffiths, RSzczech, LKaye, KStryjewski, MReller, LSchulman, KCorey, GFowler, V OBJECTIVE: To examine the clinical outcomes and costs associated with Staphylococcus aureus bacteremia among hemodialysis-dependent patients. DESIGN: Prospectively identified cohort study. SETTING: A tertiary-care university medical center in North Carolina. PATIENTS: Two hundred ten hemodialysis-dependent adults with end-stage renal disease hospitalized with S. aureus bacteremia. RESULTS: The majority of the patients (117; 55.7%) underwent dialysis via tunneled catheters, and 29.5% (62) underwent dialysis via synthetic arteriovenous fistulas. Vascular access was the suspected source of bacteremia in 185 patients (88.1%). Complications occurred in 31.0% (65), and the overall 12-week mortality rate was 19.0% (40). The mean cost of treating S. aureus bacteremia, including readmissions and outpatient costs, was $24,034 per episode. The mean initial hospitalization cost was significantly greater for patients with complicated versus uncomplicated S. aureus bacteremia ($32,462 vs $17,011; P = .002). CONCLUSION: Interventions to decrease the rate of S. aureus bacteremia are needed in this high-risk, hemodialysis-dependent population.
spellingShingle Engemann, J
Friedman, J
Reed, S
Griffiths, R
Szczech, L
Kaye, K
Stryjewski, M
Reller, L
Schulman, K
Corey, G
Fowler, V
Clinical outcomes and costs due to Staphylococcus aureus bacteremia among patients receiving long-term hemodialysis.
title Clinical outcomes and costs due to Staphylococcus aureus bacteremia among patients receiving long-term hemodialysis.
title_full Clinical outcomes and costs due to Staphylococcus aureus bacteremia among patients receiving long-term hemodialysis.
title_fullStr Clinical outcomes and costs due to Staphylococcus aureus bacteremia among patients receiving long-term hemodialysis.
title_full_unstemmed Clinical outcomes and costs due to Staphylococcus aureus bacteremia among patients receiving long-term hemodialysis.
title_short Clinical outcomes and costs due to Staphylococcus aureus bacteremia among patients receiving long-term hemodialysis.
title_sort clinical outcomes and costs due to staphylococcus aureus bacteremia among patients receiving long term hemodialysis
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