Adrenaline stimulates glucagon secretion by Tpc2-dependent Ca2+ mobilization from acidic stores in pancreatic α-cells
Adrenaline is a powerful stimulus of glucagon secretion. It acts by activation of β-adrenergic receptors but the downstream mechanisms have only been partially elucidated. Here we have examined the effects of adrenaline in mouse and human α-cells by a combination of electrophysiology, imaging of Ca2...
| Main Authors: | , , , , , , , , , , , , , , , , |
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| 格式: | Journal article |
| 语言: | English |
| 出版: |
American Diabetes Association
2018
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