The genetic architecture of type 2 diabetes

The genetic architecture of common traits, including the number, frequency, and effect sizes of inherited variants that contribute to individual risk, has been long debated. Genome-wide association studies have identified scores of common variants associated with type 2 diabetes, but in aggregate, t...

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Hlavní autoři: McCarthy, D, Mahajan, A, Gaulton, K, Moutsianas, L, Rivas, M, Perry, J, Robertson, N, Rayner, N, Tajes, J, Lindgren, C, Beer, N, van de Bunt, M, Pearson, R, Kumar, A, Chen, Y, Ferreira, T, Horikoshi, M, Levy, J, Groves, C, Ingelsson, E, Neville, M, Farmer, A, Karpe, F, Blancher, C, Buck, G, Trakalo, J, Buck, D, Prokopenko, I, Owen, K, Gloyn, A, Donnelly, P, McVean, G, Morris, A, McCarthy, M
Médium: Journal article
Vydáno: Nature Publishing Group 2016