A phosphodiesterase 3B-based signaling complex integrates exchange protein activated by cAMP 1 and phosphatidylinositol 3-kinase signals in human arterial endothelial cells.

A phosphodiesterase 3B-based signaling complex integrates exchange protein activated by cAMP 1 and phosphatidylinositol 3-kinase signals in human arterial endothelial cells.

Enzymes of the phosphodiesterase 3 (PDE3) and PDE4 families each regulate the activities of both protein kinases A (PKAs) and exchange proteins activated by cAMP (EPACs) in cells of the cardiovascular system. At present, the mechanisms that allow selected PDEs to individually regulate the activities...

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Những tác giả chính:	Wilson, L, Baillie, G, Pritchard, L, Umana, B, Terrin, A, Zaccolo, M, Houslay, MD, Maurice, D
Định dạng:	Journal article
Ngôn ngữ:	English
Được phát hành:	2011

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