A phosphodiesterase 3B-based signaling complex integrates exchange protein activated by cAMP 1 and phosphatidylinositol 3-kinase signals in human arterial endothelial cells.

Enzymes of the phosphodiesterase 3 (PDE3) and PDE4 families each regulate the activities of both protein kinases A (PKAs) and exchange proteins activated by cAMP (EPACs) in cells of the cardiovascular system. At present, the mechanisms that allow selected PDEs to individually regulate the activities...

詳細記述

書誌詳細
主要な著者: Wilson, L, Baillie, G, Pritchard, L, Umana, B, Terrin, A, Zaccolo, M, Houslay, MD, Maurice, D
フォーマット: Journal article
言語:English
出版事項: 2011