Synthesis and biological action of novel 4-position-modified derivatives of D-myo-inositol 1,4,5-trisphosphate.

The design of a range of 4-position-modified D-myo-inositol 1,4,5-trisphosphate derivatives is described. The enantioselective synthesis of these compounds is reported, along with initial biological analysis, which indicates that these compounds do not act as D-myo-inositol 1,4,5-trisphosphate recep...

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Main Authors: Bello, D, Aslam, T, Bultynck, G, Slawin, A, Roderick, H, Bootman, MD, Conway, S
Format: Journal article
Language:English
Published: 2007
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author Bello, D
Aslam, T
Bultynck, G
Slawin, A
Roderick, H
Bootman, MD
Conway, S
author_facet Bello, D
Aslam, T
Bultynck, G
Slawin, A
Roderick, H
Bootman, MD
Conway, S
author_sort Bello, D
collection OXFORD
description The design of a range of 4-position-modified D-myo-inositol 1,4,5-trisphosphate derivatives is described. The enantioselective synthesis of these compounds is reported, along with initial biological analysis, which indicates that these compounds do not act as D-myo-inositol 1,4,5-trisphosphate receptor agonists or antagonists.
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spelling oxford-uuid:fa80ee60-0cc1-4777-a6f0-ae633186e5a02022-03-27T13:06:23ZSynthesis and biological action of novel 4-position-modified derivatives of D-myo-inositol 1,4,5-trisphosphate.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:fa80ee60-0cc1-4777-a6f0-ae633186e5a0EnglishSymplectic Elements at Oxford2007Bello, DAslam, TBultynck, GSlawin, ARoderick, HBootman, MDConway, SThe design of a range of 4-position-modified D-myo-inositol 1,4,5-trisphosphate derivatives is described. The enantioselective synthesis of these compounds is reported, along with initial biological analysis, which indicates that these compounds do not act as D-myo-inositol 1,4,5-trisphosphate receptor agonists or antagonists.
spellingShingle Bello, D
Aslam, T
Bultynck, G
Slawin, A
Roderick, H
Bootman, MD
Conway, S
Synthesis and biological action of novel 4-position-modified derivatives of D-myo-inositol 1,4,5-trisphosphate.
title Synthesis and biological action of novel 4-position-modified derivatives of D-myo-inositol 1,4,5-trisphosphate.
title_full Synthesis and biological action of novel 4-position-modified derivatives of D-myo-inositol 1,4,5-trisphosphate.
title_fullStr Synthesis and biological action of novel 4-position-modified derivatives of D-myo-inositol 1,4,5-trisphosphate.
title_full_unstemmed Synthesis and biological action of novel 4-position-modified derivatives of D-myo-inositol 1,4,5-trisphosphate.
title_short Synthesis and biological action of novel 4-position-modified derivatives of D-myo-inositol 1,4,5-trisphosphate.
title_sort synthesis and biological action of novel 4 position modified derivatives of d myo inositol 1 4 5 trisphosphate
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