Halofantrine pharmacokinetics in Kenyan children with non-severe and severe malaria.

Halofantrine pharmacokinetics in Kenyan children with non-severe and severe malaria.

1. Kenyan children with uncomplicated malaria given oral halofantrine (HF; non-micronised suspension; 8 mg base kg-1 body weight 6 hourly for three doses) showed wide variation in the disposition of HF and desbutylhalofantrine (HFm). 2. Eight Kenyan children with severe (prostrate) falciparum malari...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид:	Watkins, WM, Winstanley, P, Mberu, E, Kokwaro, G, Murphy, SA, Newton, C, Mwangi, I, Forster, D, Marsh, K
Формат:	Journal article
Хэл сонгох:	English
Хэвлэсэн:	1995

Ижил төстэй зүйлс

The disposition of oral and intramuscular pyrimethamine/sulphadoxine in Kenyan children with high parasitaemia but clinically non-severe falciparum malaria.
-н: Winstanley, P, зэрэг
Хэвлэсэн: (1992)

A single dose of intramuscular sulfadoxine-pyrimethamine as an adjunct to quinine in the treatment of severe malaria: pharmacokinetics and efficacy.
-н: Newton, C, зэрэг
Хэвлэсэн: (1993)

Epileptic seizures and malaria in Kenyan children.
-н: Waruiru, C, зэрэг
Хэвлэсэн: (1996)

Prophylactic phenobarbitone in young children with severe falciparum malaria: pharmacokinetics and clinical effects.
-н: Winstanley, P, зэрэг
Хэвлэсэн: (1992)

Pharmacokinetics and clinical efficacy of midazolam and lorazepam in Kenyan children with severe malaria and convulsions [MIM-MN-175440]
-н: Muchohi, S, зэрэг
Хэвлэсэн: (2005)

Pharmacokinetics and clinical effects of phenytoin and fosphenytoin in children with severe malaria and status epilepticus.
-н: Ogutu, B, зэрэг
Хэвлэсэн: (2003)

Chloramphenicol pharmacokinetics in African children with severe malaria.
-н: Kokwaro, G, зэрэг
Хэвлэсэн: (2006)

Photographic and angiographic characterization of the retina of Kenyan children with severe malaria.
-н: Hero, M, зэрэг
Хэвлэсэн: (1997)

Hypoglycaemia on and after admission in Kenyan children with severe malaria.
-н: English, M, зэрэг
Хэвлэсэн: (1998)

Pharmacokinetics, efficacy and toxicity of parenteral halofantrine in uncomplicated malaria.
-н: Krishna, S, зэрэг
Хэвлэсэн: (1993)

Pharmacokinetics and clinical efficacy of midazolam in children with severe malaria and convulsions.
-н: Muchohi, SN, зэрэг
Хэвлэсэн: (2008)

Halofantrine in the treatment of malaria.
-н: Horton, J
Хэвлэсэн: (1995)

Pharmacokinetics and anticonvulsant effects of diazepam in children with severe falciparum malaria and convulsions.
-н: Ogutu, B, зэрэг
Хэвлэсэн: (2002)

Pharmacokinetics and clinical efficacy of lorazepam in children with severe malaria and convulsions.
-н: Muchohi, SN, зэрэг
Хэвлэсэн: (2008)

Severe P. falciparum malaria in Kenyan children: evidence for hypovolaemia.
-н: Maitland, K, зэрэг
Хэвлэсэн: (2003)

Population pharmacokinetics of halofantrine in healthy volunteers and patients with symptomatic falciparum malaria
-н: Klein, K, зэрэг
Хэвлэсэн: (2012)

Population pharmacokinetics of halofantrine in healthy volunteers and patients with symptomatic falciparum malaria.
-н: Klein, K, зэрэг
Хэвлэсэн: (2012)

Pharmacokinetics and clinical effect of phenobarbital in children with severe falciparum malaria and convulsions.
-н: Kokwaro, G, зэрэг
Хэвлэсэн: (2003)

Towards optimal regimens of parenteral quinine for young African children with cerebral malaria: unbound quinine concentrations following a simple loading dose regimen.
-н: Winstanley, P, зэрэг
Хэвлэсэн: (1994)

The treatment of falciparum malaria in children with halofantrine suspension
-н: R. J. Horton, зэрэг
Хэвлэсэн: (1992-01-01)

Coma scales for children with severe falciparum malaria.
-н: Newton, C, зэрэг
Хэвлэсэн: (1997)

Pharmacology of absorption and distribution: optimal use of antimalarial drugs in the treatment of severe falciparum malaria in Kenya.
-н: Watkins, WM, зэрэг
Хэвлэсэн: (1994)

Arginine vasopressin secretion in Kenyan children with severe malaria.
-н: Sowunmi, A, зэрэг
Хэвлэсэн: (2000)

Speech and language sequelae of severe malaria in Kenyan children.
-н: Carter, J, зэрэг
Хэвлэсэн: (2003)

Oxidative stress and erythrocyte damage in Kenyan children with severe Plasmodium falciparum malaria.
-н: Griffiths, M, зэрэг
Хэвлэсэн: (2001)

Halofantrine in the treatment of multidrug resistant malaria
-н: Philip Davis Marsden
Хэвлэсэн: (1989-09-01)

Halofantrine in the treatment of multidrug resistant malaria
-н: Philip Davis Marsden
Хэвлэсэн: (1989-09-01)

Population pharmacokinetics of artemether and dihydroartemisinin following single intramuscular dosing of artemether in African children with severe falciparum malaria.
-н: Mithwani, S, зэрэг
Хэвлэсэн: (2004)

Quinine treatment of severe falciparum malaria in African children: a randomized comparison of three regimens.
-н: Pasvol, G, зэрэг
Хэвлэсэн: (1991)

The management of severe malaria in children: a review.
-н: Murphy, S, зэрэг
Хэвлэсэн: (1995)

The disposition of intramuscular artemether in children with cerebral malaria; a preliminary study.
-н: Murphy, SA, зэрэг
Хэвлэсэн: (1997)

Cerebrospinal Fluid Studies in Kenyan Children with Severe Falciparum Malaria.
-н: Mturi, N, зэрэг
Хэвлэсэн: (2008)

Parasite viability during treatment of severe falciparum malaria: differential effects of artemether and quinine.
-н: Murphy, S, зэрэг
Хэвлэсэн: (1995)

Brain swelling and ischaemia in Kenyans with cerebral malaria.
-н: Newton, C, зэрэг
Хэвлэсэн: (1994)

Seizure disorders among relatives of Kenyan children with severe falciparum malaria.
-н: Versteeg, A, зэрэг
Хэвлэсэн: (2003)

Perturbations in electrolyte levels in kenyan children with severe malaria complicated by acidosis.
-н: Maitland, K, зэрэг
Хэвлэсэн: (2005)

Axonal and astrocyte injury markers in the cerebrospinal fluid of Kenyan children with severe malaria.
-н: Medana, I, зэрэг
Хэвлэсэн: (2007)

Persistent neurocognitive impairments associated with severe falciparum malaria in Kenyan children.
-н: Carter, J, зэрэг
Хэвлэсэн: (2005)

Very low mortality associated with albumin infusion in Kenyan children with severe malaria
-н: Maitland, K, зэрэг
Хэвлэсэн: (2006)

Indicators of life-threatening malaria in African children.
-н: Marsh, K, зэрэг
Хэвлэсэн: (1995)